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ea0035oc11.3 | Diabetes and Obesity 2 | ECE2014

Improvement or stabilization of retinopathy and visual acuity after islet transplantation: a 5-year prospective study

Vantyghem Marie-Christine , Quintin Delphine , Labalette Pierre , Kerr-Conte Julie , Pattou Francois

This study describes the evolution of retinopathy 5 years after islet transplantation (IT) with the Edmonton protocol in type 1 diabetic patients. Before IT and then yearly for 5 years, 21 patients (13 islet-alone (ITA), 8 islet-after-kidney (IAK)) underwent monitoring of laboratory parameters, continuous 24 h mean blood pressure (24h BP) and 72 h glucose (CGM), as well as complete ophthalmologic examination. Ten of the 21 patients (48%) were insulin-independent 5 years post-I...

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ea0035oc11.5 | Diabetes and Obesity 2 | ECE2014

Lipodystophic laminopathies are characterised by an increased intra/whole abdominal fat ratio with preserved fat/lean mass ratio and hypoleptinemia, in contrast with obese people, compared to controls

Le Mapihan Kristell , Leroy Clara , Ernst Olivier , Vigouroux Corinne , Lion Georges , Le Guillou Anne-Claire , Quintin Delphine , Douillard Claire , Vantyghem Marie-Christine

Introduction: The diagnosis of non-HIV lipodystrophies is challenging, especially since borderline forms with type 2 diabetes have been described (Strickland Diabetes Care 2013).Objective: To identify the most specific anthropometric and biological parameters enabling to differentiate lipodystrophic from obese and control subjects.Methods: This prospective study (clin.gov 2009-AO-1169-48) included 94 patients divided in 3 groups ad...

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Endocrine Abstracts

Improvement or stabilization of retinopathy and visual acuity after islet transplantation: a 5-year prospective study

Lipodystophic laminopathies are characterised by an increased intra/whole abdominal fat ratio with preserved fat/lean mass ratio and hypoleptinemia, in contrast with obese people, compared to controls

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